News
Automatically gathered and summarized from longevity-focused publications, with links to the original reporting.
lifespan.io · Jul 24, 2026
NYC Woman Dead After Receiving a “Longevity Infusion”According to the experts that we spoke to, the death, which followed an intravenous NAD⁺ infusion that went catastrophically wrong, underscores the risks of unproven treatments and the need for rigorous longevity medicine.
Read original →longevity.technology · Jul 24, 2026
Rani Therapeutics broadens obesity pipeline with PegBio dealCollaboration adds multiple potential obesity drug candidates to Rani’s pipeline while advancing ambition to replace injections with pills. One of the biggest barriers to treatment for many people living with obesity is how medicines are delivered.
Read original →longevity.technology · Jul 24, 2026
Brain scans hint at new way to slow Alzheimer’sNew data suggest LM11A-31 may help preserve the brain’s communication networks, offering another promising path in Alzheimer’s research. The race against Alzheimer’s disease has largely revolved around amyloid plaques.
Read original →longevity.technology · Jul 24, 2026
HCW Biologics prepares to bring new cancer therapy into human trials - Longevity.TechnologyLongevity.Technology is growing fast; we are open to conversations with prospective partners and investors who share our vision. Please get in touch if you are interested: HCW Biologics has requested a Type B pre-Investigational New Drug meeting with the U.S.
Read original →longevity.technology · Jul 24, 2026
Insilico Medicine unveils AI-designed drug candidate for chronic and surgical pain - Longevity.TechnologyLongevity.Technology is growing fast; we are open to conversations with prospective partners and investors who share our vision. Please get in touch if you are interested: Insilico Medicine nominated ISM9528 as a Preclinical Candidate Compound for pain management, targeting what the company describes as a $100 billion market.
Read original →longevity.technology · Jul 24, 2026
Serina Therapeutics completes cohort 1 dosing in Parkinson's trial - Longevity.TechnologyLongevity.Technology is growing fast; we are open to conversations with prospective partners and investors who share our vision.
Read original →longevity.technology · Jul 24, 2026
Health Optimisation Summit adds business focusLondon event expands as founders, investors and clinicians gather alongside researchers to explore the future of preventive health. After a sold-out event in 2025, the Health Optimisation Summit will return to London’s Business Design Centre on 11–13 September with a noticeably broader remit.
Read original →lifespan.io · Jul 23, 2026
More Autophagy Reduces Toxin-Induced Kidney Failure in MiceAutophagy, which increases in younger mice under toxic stress, does not increase in older mice and leaves them susceptible to acute kidney injury (AKI) . Increasing autophagic flux by targeting a key molecule, transcription factor EB (TFEB), alleviates some of this damage.
Read original →longevity.technology · Jul 23, 2026
Is personalized nutrition worth it?As personalized nutrition grows, experts argue the smartest health strategy may be simple: test first, supplement second. Walk into any health store or scroll through social media for five minutes and you’ll quickly get the impression that longevity comes in capsule form. Magnesium for sleep. Creatine for strength. Vitamin D for immunity.
Read original →longevity.technology · Jul 23, 2026
Vandria’s experimental Alzheimer’s pill proves safe, reaches target in first human study - Longevity.TechnologyLongevity.Technology is growing fast; we are open to conversations with prospective partners and investors who share our vision. Please get in touch if you are interested: Lausanne-based Vandria presented multiple ascending-dose Phase 1 data for oral small molecule VNA-318 at the Alzheimer’s Association International Conference in London.
Read original →longevity.technology · Jul 23, 2026
Ultrahuman unveils its biggest longevity platform overhaulThe Emerald update redesigns the app around actionable health insights, bringing smarter guidance for everyday longevity. Can wearables finally answer the question: What now? If you’ve ever worn a fitness tracker, you’ve probably experienced a familiar feeling. You wake up, check your app and discover you slept poorly. Your stress score is higher than yesterday. Your recovery isn’t great.
Read original →longevity.technology · Jul 23, 2026
Timeline wins $5.3m in fake urolithin A caseFederal court ruling highlights growing pressure for quality assurance as longevity interventions move into increasingly crowded market.
Read original →lifespan.io · Jul 22, 2026
The Progress and Future of Biological Aging ClocksA recent review discusses the development of biological aging clocks, their capabilities and limitations, the discoveries they enabled, and possible future developments in this area [1].
Read original →lifespan.io · Jul 21, 2026
Gabriel Cian on Building the 2060 Longevity EcosystemIn this follow-up interview, we speak with Gabriel Cian about how the 2060 ecosystem has evolved since last year’s Forum , what he learned from the first edition, and how he is thinking about investment, scientific credibility, health optimization, policy, and the future of longevity in Europe.
Read original →lifespan.io · Jul 21, 2026
Regular Training Erases Parts of Muscle Aging SignatureA new study suggests that regular planned exercise, not just being generally active, protects against certain aspects of muscle aging [1]. Are trained muscles younger? With age, skeletal muscles lose strength, metabolic flexibility, and mitochondrial capacity.
Read original →lifespan.io · Jul 20, 2026
Exosomes From Stem Cells Fight Liver Disease in MiceResearchers have described a method of using exosomes derived from mesenchymal stem cells (MSCs) to fight harmful metabolic changes in the liver . Another look at exosomes This is far from the first attempt at using MSC-derived exosomes, particularly exosomes derived from MSCs originally taken from human umbilical cord tissue (HucMDEs derived from HucMSCs), to treat an age-related disease.
Read original →fightaging.org · Jul 17, 2026
Small Molecule GPR40 Agonism Restores Thymic Activity in Aged MiceThe thymus is a tiny organ near the heart responsible for generating T cells of the adaptive immune system . Thymocyte cells are made in the bone marrow, migrate to the thymus, and undergo a process of exposure and selection that leads to mature T cells. The adaptive immune system needs a supply of new cells to make up the losses incurred due to damage and the Hayflick limit on replication.
Read original →fightaging.org · Jul 17, 2026
SORLA Upregulation as a Possible Means to Treat TauopathiesJuly 24th, 2026 A number of neurodegenerative conditions , including Alzheimer's disease , are characterized by a pervasive chemical alteration of tau protein that causes tau to cease its normal function and aggregate into structures known as neurofibrillary tangles . This is harmful to neurons and their normal, necessary function.
Read original →fightaging.org · Jul 17, 2026
Senescent Cells Accumulate Lipid Droplets in the Aging BrainJuly 24th, 2026 One of the hallmarks of dysfunctional lipid metabolism in the brain the context of age-related neurodegenerative disease is an increase in lipid droplets in brain cells. This is seen in a number of different neurodegenerative conditions.
Read original →lifespan.io · Jul 17, 2026
Engineered Enzyme Reverses Age-Related Protein DamageScientists have engineered an enzyme that removes an advanced glycation end product (AGE) from proteins . This type of age-related modification, which affects protein function and can trigger inflammation, has previously been considered extremely hard to reverse [1]. Can we rejuvenate proteins? Many proteins are continually broken down and replaced.
Read original →fightaging.org · Jul 16, 2026
A View of Aging Centered Around the Role of Karyopherins and Nuclear TransportJuly 23rd, 2026 The biochemistry of aging is enormously complex, and it is very hard to pick apart which changes are definitively cause versus effect, and which changes are definitively more important than others. The only robust approach is to build a therapy that fixes just one change in isolation, and observe the results. This is not always possible or practical.
Read original →lifespan.io · Jul 16, 2026
Activating a Key Receptor Fights Thymic Involution in MicePublishing in Aging Cell , researchers have devised a way to delay the aging of the thymus by targeting GPR40, a key receptor in its epithelial cells . The organ that involutes The thymus trains a certain subset of immune cells, which are named T cells due to their relationship with it.
Read original →fightaging.org · Jul 16, 2026
Gut Microbiome Composition Correlates with Epigenetic Clock ResultsJuly 23rd, 2026 The gut microbiome changes with age in ways the provoke chronic inflammation and tissue dysfunction. Animal studies demonstrate that restoring a youthful gut microbiome to old individuals extends life and improves health. Thus we would expect favorable changes to the gut microbiome to be reflected in any good alternative measure of aging, such as aging clocks .
Read original →fightaging.org · Jul 16, 2026
Reviewing Age-Related Changes in MicrogliaJuly 23rd, 2026 Microglia are innate immune cells resident in the brain, analogous to macrophages elsewhere in the body. Like macrophages, microglia are deeply involved in tissue maintenance as well as defense against pathogens and destruction of potentially cancerous, malfunctioning cells. Microglia adopt different packages of behaviors, called polarizations .
Read original →lifespan.io · Jul 15, 2026
Forever Healthy Launches Evipedia AI IntegrationToday, Forever Healthy announces the launch of a set of new tools to make it easier than ever for AI agents, research pipelines, and AI environments to integrate Evipedia. Evipedia is Forever Healthy’s comprehensive, continuously updated online encyclopedia dedicated to providing much-needed, accurate, and up-to-date information on a wide range of health and longevity-related interventions.
Read original →fightaging.org · Jul 15, 2026
How to Go About Measuring Health in Aging is its Own Sizable DebateJuly 22nd, 2026 Health is like art; one knows it if one sees it. But that isn't good enough for the development of therapies. Health must be pinned down and actually measured. Numerous bodies have offered guidelines to this end, and those guidelines have been interpreted in countless different ways by the scientists who conduct studies.
Read original →fightaging.org · Jul 15, 2026
Quantifying the Risk of Alzheimer's Disease Associated with High Levels of p-tau217 in BloodJuly 22nd, 2026 The first predictive blood tests for future risk of Alzheimer's disease were developed in recent years based on correlations between marker proteins in the blood and disease risk derived from large epidemiological studies. One such marker is phosphorylated tau 217 (p-tau217) , a modified variant of the tau protein involved in Alzheimer's disease pathology.
Read original →fightaging.org · Jul 15, 2026
CMLase Enzyme Developed to Break Down CML Advanced Glycation EndproductsJuly 22nd, 2026 Advanced glycation endproducts (AGEs) are a broad class of sugar-modified molecules that have harmful effects in the body.
Read original →fightaging.org · Jul 14, 2026
The Aging Immune System Disrupts Maintenance of Bone TissueJuly 21st, 2026 As for all tissues, bone derives its structural properties from the composition and structure of its extracellular matrix . This matrix constantly undergoes dynamic modification: osteoclast cells break down the matrix, while osteoblast cells build it up.
Read original →lifespan.io · Jul 14, 2026
Peripheral Inflammation May Drive Parkinson’sA new study suggests that aging or Parkinson’s-triggering mutations create inflammation in peripheral tissues, and then circulating extracellular vesicles spread it to the brain, which might contribute to the disease [1]. Brain on fire Nature made the brain remarkably well-protected, including from the elements by the skull and from pathogens by the blood-brain barrier (BBB).
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